SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Israel/EPI_IS

SARS-CoV-2 Spike Trimer Protein, His Tag (BA.2.86/Israel/EPI_ISL_18096761) (SPN-C524w) is expressed from human 293 cells (HEK293). It contains AA Val 16 - Pro 1213 (Accession # QHD43416.1 (ins16MPLF,T19I,R21T,LPP24-26Del,A27S,S50L,H69del,V70del,V127F,G142D,Y144del,F157S,R158G,N211del,L212I,V213G,L216F,H245N,A264D,I332V,G339H,K356T,S371F,S373P,S375F,T376A,R403K,D405N,K417N,N440K,V445H,G446S,N450D,L452W,N460K,S477N,T478K,N481K,V483del,E484K,F486P,Q498R,N501Y,Y505H,A570V,D614G,P621S,H655Y,I670V,N679K,P681R,N764K,D796Y,S939F,Q954H,N969K,P1143L,R683A, R685A, F817P, A892P, A899P, A942P, K986P, V987P)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.86/Israel/EPI_ISL_18096761). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.

Product #: SPN-C524w-500ug-202 Unit size: 500ug*1 CAS #: N/A UNSPSC: N/A Supplier: ACROBiosystems Available in the following countries: