Human CD64 (Luc) Jurkat Reporter Cell

Fcγ receptors (FcγRs), the largest group of FcRs, bind IgG and comprise several subtypes. FcγRI (CD64), a high-affinity receptor that binds monomeric uncomplexed IgG molecules. FcγRI saturation by endogenous circulating IgGs in vivo may attenuate its role in mediating antibody function.