Human CD32a (131H) (Luc) Jurkat Reporter Cell

ADCP is the mechanism by which antibody-opsonized target cells activate the FcγRs on the surface of macrophages to induce phagocytosis, resulting in internalization and degradation of the target cell through phagosome acidification. ADCP is mediated by FcγIIa (CD32a)-activated macrophages leading to augmented phagocytosis.