Anti-Rituximab Antibody (MALS verified)

Rituxan is a genetically engineered chimeric murine/human monoclonal antibody directed against the CD20 antigen found on the surface of normal and malignant B lymphocytes. The antibody is an IgG1 kappa immunoglobulin containing murine light- and heavy-chain variable region sequences and human constant region sequences. Rituximab is composed of two heavy chains of 451 amino acids and two light chains of 213 amino acids, Anti-Rituximab Antibodies (RIB-Y35c) is the monoclonal antibody of Rituximab expressed with human HEK293 cells.