APC-Labeled Human HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Tetramer

MHC Class I molecules are expressed on nearly all nucleated cells and present peptides to cytotoxic T-cells (CD8+) to survey for infected or cancerous cells. MAGE-A4 is normally silent in adult tissues (except testes and placenta) but is aberrantly expressed in various tumors (e.g., melanoma, lung cancer), making it a prime target for cancer immunotherapy, including T-cell therapies and vaccines.