Products include nucleosides, nucleotides and their non-natural analogs, recombinant proteins & protein production systems, reagents for the crystallization of biological macromolecules and tailor-made solutions for molecular biology and biochemistry.

• Nucleosides, Nucleotides and their Analogs
  Nucleotides
  Natural nucleotides and modified analogs, such as non-hydrolyzable derivatives, nucleotides containing fluorescent groups or halogen atoms and much more
  Nucleotide Libraries & Kits
  Libraries of Nucleotide analogs for drug screening and nucleotide kits for a plethora of applications
  Nucleosides
  Modified nucleoside analogs (i.e. nucleobase linked to a sugar moiety but lacking the phosphate groups)
  Nucleoside Phosphoramidites
  Phosphoramidites used to synthesize oligonucleotides by automated standard protocols
• Click Chemistry Reagents
  Click chemistry is a chemical paradigm introduced by K. Barry Sharpless in 2001  and describes chemical reactions that generate substances quickly, reliably and in quantitative yield by joining small building blocks under mild conditions. This is inspired by the fact that chemical reactions in nature also generate substances by joining small modular units.

  Advantages of click chemistry labeling: Labeling by simple, efficient reactions High labeling yield (nearly quantitative) Allows introduction of sensitive labels (mild conditions) Highly modular system (combinatorial approach) Orthogonal to conventional methods Bioorthogonal reaction (no azides or alkynes in natural systems) Labeling of all bases possible (G, A, C, T, U) Broad range of marker- and dye-azides available Also adaptable to linking beads, microarrays, nanoparticles, peptides etc

• Molecular Biology
  

  Real-Time PCR Standard PCR Reverse Transcription in vitro Transcription Ready-to-Use Lyophilisates Primers and Oligonucleotides Buffers and Reagents

  DNA Labeling and Modification Cloning and Mutagenesis RNA / DNA Preparation and Cleanup DNA Sequencing (Sanger Method) DNA Ladders Protein MW Markers / Gel Staining Restriction/Modifying Enzymes

• Eukaryotic Expression System LEXSY
  

  The unicellular kinetoplast protozoan Leishmania tarentolae, isolated from the Moorish gecko Tarentola mauritanica, not pathogenic to mammalians (Biosafety level 1) – was turned into the protein-producing host of our eukaryotic protein expression system LEXSY:

  • eukaryotic host as easy to handle as E. coli: no specific labware, no cell biology equipment required
  • fully eukaryotic protein expression machinery with post-translational modifications, including glycosylation and disulfide bond formation
  • shuttle vectors: cloning in E. coli, expression in LEXSY host
  • constitutive or inducible, intracellular or secretory expression of target proteins
  • stable expression strains for constant protein production
• Affinity Chromatography
  The ability to purify recombinant proteins using affinity chromatography has greatly advanced protein research. In affinity chromatography, the protein of interest is purified by its ability to bind a specific ligand that is immobilized on a chromatographic bead material (matrix). Crude cell-lysates are incubated with such a matrix under conditions that ensure specific binding of the protein to the immobilized ligand. Other proteins that do not bind the immobilized ligand are washed through. Elution of the bound protein of interest can be achieved by changing the experimental conditions to favour desorption. Jena Bioscience offers both Agarose and Magnetic Beads as matrix for different purification tasks.
  
• Biochemistry
• Macromolecular Crystallography
• Fluorescent Probes
  Fluorescent Dyes
  NHS Esters, Azides, Alkyne-, DBCO- and Tetrazine-derivatives of fluorescent dyes for labeling of biomoleculesProtein Labeling
  Novel luminescent protein labels and approved versatile kits for protein labelingDNA Labeling
  Fluorescent nucleotides and oligos, DNA labeling kits and much moreRNA Labeling
  Ready-to-use Labeling kits for fluorescent labeling of RNA probes with thoroughly selected Atto-dyesKinase Assays
  Fluorescent Anisotropy Assay to identify potential kinase inhibitorsFluorescent Hormones
  Fluorescently labeled bioactive hormones, such as Estradiol

  evoglow^® – Anaerobic Fluorescent Proteins
  Anaerobic fluorescent proteins and corresponding antibodies